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 HBV type 3 PreS1 (aa 1 - 445) [BSA] 

HBV type 3 PreS1 (aa 1 - 445) [BSA]

(October 26, 2018)

HBsAg is the surface antigen of the hepatitis B virus (HBV). It indicates current hepatitis B infection.The viral envelope of enveloped virus has different surface proteins from the rest of the virus which act as antigens. These antigens are recognized by antibody proteins that bind specifically to one of these surface proteins.The HBsAg gene is one long open reading frame but contains three in frame "start" (ATG) codons that divide the gene into three sections, pre-S1, pre-S2, and S. B

[Related Keywords: HBV type 3 PreS1 (aa 1 - 445) [BSA] ]

 HBV Surface Antigen (subtype ayw, mutation G-145-R) 

HBV Surface Antigen (subtype ayw, mutation G-145-R)

(October 26, 2018)

Hepatitis B Virus (HBV) infection inducesa disease state characterised by liver damage, inflammation and viralpersistence. Infection also increases the risk of hepatocellular carcinoma.HBV belongs to the Hepadnaviridae family of viruses. Its genome consists ofpartially double stranded circular DNA. The DNA is enclosed in anucleocapsid, or core antigen (HBcAg), which is surrounded by a sphericalenvelope (surface antigen or HBsAg). The core antigen shares its sequenceswith the e antigen (HBeAg) but no c

[Related Keywords: HBV Surface Antigen ]

 HBV Active Antigen 

HBV Active Antigen

(October 26, 2018)

Hepatitis B Virus Core Antigen (HBcAg) is part of the infectious virion containing an inner "core particle" enclosing the viral genome. The icosahedral core particle contains 180 or 240 copies of the core protein. HBcAg is one of the three major clinical antigens of hepatitis B virus but disappears early in the course of infection. The hepatitis B virus core antigen (HBcAg) is a highly immunogenic subviral particle and functions as both a T-cell-dependent and a T-cell-inde

[Related Keywords: HBV Active Antigen ]

 Recombinant Hepatitis B E Antigen, His-tagged 

Recombinant Hepatitis B E Antigen, His-tagged

(October 26, 2018)

Hepatitis B e-antigen (HBeAg) is a viral protein associated with HBV infections. Unlike the surface antigen, the e-antigen is found in the blood only when there are viruses also present. When the virus goes into hiding, the e-antigen will no longer be present in the blood. HBeAg is often used as a marker of ability to spread the virus to other people (infectivity). Measurement of e-antigen may also be used to monitor the effectiveness of HBV treatment; successful treatment will usually eliminate HBeAg

[Related Keywords: Recombinant Hepatitis B E Antigen ]

 HBV Surface Antigen 

HBV Surface Antigen

(October 26, 2018)

The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.



[Related Keywords: HBV Surface Antigen ]
 HCMV Interleukin 10 (aa 26 - 176) 

HCMV Interleukin 10 (aa 26 - 176)

(October 26, 2018)

Interleukin-10 (IL-10) is a pleiotropic cytokine that plays a crucial role in regulating immune and inflammstory responses. It has closely related homologs in the genome of several viruses including the human cytomegalovirus (HCMV), a prevalent pathogen t. https://www.creative-diagnostics.com/Recombinant-Viral-HCMV-IL-10-105931-340.htm.



[Related Keywords: HCMV Interleukin 10 ]
 HCMV (AB 32/32) [His] 

HCMV (AB 32/32) [His]

(October 26, 2018)

Cytomegalovirus (CMV), is a genus of Herpes viruses; in humans the species is known as Human herpesvirus 5 (HHV-5). It belongs to the Betaherpesvirinae subfamily of Herpesviridae. The name means "very big cell virus". https://www.creative-diagnostics.com/HCMV-AB-32-32-125044-340.htm.



[Related Keywords: HCMV (AB 32/32) [His] ]
 HCV type 1 Core Antigen (aa 1 - 102) 

HCV type 1 Core Antigen (aa 1 - 102)

(October 26, 2018)

The hepatitis C virus (HCV) core protein represents the first 191 amino acids of the viral precursor polyprotein and is cotranslationally inserted into the membrane of the endoplasmic reticulum. Hepatitis C virus (HCV) core is a viral structural protein; it also participates in some cellular processes, including transcriptional regulation. However the mechanisms of core-mediated transcriptional regulation remain poorly understood. Hepatitis C virus (HCV) core protein is thought to contribute to HCV pathogenesis through its interaction with various signal transduction pathways. In addition, HCV core antigen is

[Related Keywords: HCV type 1 Core Antigen (aa 1 - 102) ]

 HCV E2 Protein (aa 383 - 663) [His] 

HCV E2 Protein (aa 383 - 663) [His]

(October 26, 2018)

E2 is a viral structural protein found in hepatitis C amongst other viruses, including HPV. As a leading supplier of antigens, Creative Diagnostics is proud to offer the highest quality antigens supported by extensive research, development, and validation. We are committed to the highest standards of product performance, and our scientists are dedicated to accelerating your discoveries. https://www.creative-diagnostics.com/Recombinant-HCV-E2-His-tagged-104869-341.htm.



[Related Keywords: HCV E2 Protein (aa 383 - 663) [His] ]
 HCV type 1b Nonstructural Protein 5 (aa 2212 - 2313) 

HCV type 1b Nonstructural Protein 5 (aa 2212 - 2313)

(October 26, 2018)

NS5 (non structural protein 5) may play a role in the viral RNA replication of the Hepatitis C Virus. NS5A is a ~56 kDa pleiotropic protein with key roles in both viral RNA replication and modulation of the physiology of the host cell. It"s exact role is not currently known (2008). NS5B (non-structural protein 5B) is an RNA-dependant RNA polymerase responsible for replication of the hepatitis C viral genome, and is currently a principal target for chemotherapeutic inhibition of HCV replication.



[Related Keywords: HCV type 1b Nonstructural Protein 5 ]
 HCV Nonstructural Protein 4 

HCV Nonstructural Protein 4

(October 26, 2018)

NS4B is a small (27 kDa) hydrophobic integral membrane protein with 4 transmembrane domains. It is located within the endoplasmic reticulum and play an important role for recruitment of other viral proteins. It induces morphological changes to the endoplasmic reticulum forming a structure termed the membranous web. https://www.creative-diagnostics.com/Recombinant-HCV-Non-Structural-Protein4-Horseradish-Peroxidase-Labeled-105469-341.htm



[Related Keywords: HCV Nonstructural Protein 4 ]
 HCV type 2 Nonstructural Protein 5 

HCV type 2 Nonstructural Protein 5

(October 26, 2018)

NS5 (non structural protein 5) may play a role in the viral RNA replication of the Hepatitis C Virus. NS5A is a ~56 kDa pleiotropic protein with key roles in both viral RNA replication and modulation of the physiology of the host cell. It"s exact role is not currently known (2008). NS5B (non-structural protein 5B) is an RNA-dependant RNA polymerase responsible for replication of the hepatitis C viral genome, and is currently a principal target for chemotherapeutic inhibition of HCV replication. https://www.creative-diagnostics.com/Recombinant-HCV-Non-Structural-Protein-5-Genotype-2-105475-341.htm.

[Related Keywords: HCV type 2 Nonstructural Protein 5 ]

 HCV Multiple Antigen (aa 789 - 1867, 2322 - 2423) 

HCV Multiple Antigen (aa 789 - 1867, 2322 - 2423)

(October 26, 2018)

Hepatitis C virus is classified into six genotypes (1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6). https://www.creative-diagnostics.com/Recombinant-HCV-Multiple-Genotypes-105806-341.htm.



[Related Keywords: HCV Multiple Antigen ]
 HCV E1 protein 

HCV E1 protein

(October 26, 2018)

Envelope glycoproteins E1 and E2 are involved in virus attachment to the host cell as well as in virus endocytosis and fusion with host membrane. E2 inhibits human EIF2AK2/PKR activation, preventing the establishment of an antiviral state. E2 is a viral l. https://www.creative-diagnostics.com/E1-HCV-124069-341.htm.



[Related Keywords: HCV E1 protein ]
 HCV type 1a Nucleocapsid Core antigen (aa 2 - 119) 

HCV type 1a Nucleocapsid Core antigen (aa 2 - 119)

(October 26, 2018)

HCV is a small 50 nm, enveloped, single-stranded, positive sense RNA virus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. https://www.creative-diagnostics.com/Core-antigen-Genotype-1a-HCV-124301-341.htm.



[Related Keywords: HCV type 1a Nucleocapsid Core antigen (aa 2 - 119) ]
 HCV Nonstructural Protein 4 Mosaic (aa 1789 - 1867, 2322 - 2423) 

HCV Nonstructural Protein 4 Mosaic (aa 1789 - 1867, 2322 - 2423)

(October 26, 2018)

NS4 A/B are two of the seven nonstructural (NS) proteins making up the HCV polyprotein. The NS proteins recruit the viral genome into an RNA replication complex, which is associated with rearranged cytoplasmic membranes. https://www.creative-diagnostics.com/NS4-HCV-124332-341.htm.



[Related Keywords: HCV Nonstructural Protein 4 Mosaic (aa 1789 - 1867, 2322 - 2423) ]
 MME peptide 

MME peptide

(October 26, 2018)

This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic resid

[Related Keywords: MME peptide ]

Human MGMT peptide 

Human MGMT peptide

(October 26, 2018)

MGMT (O6 methylguanine DNA methyltransferase) is an enzyme that transfers methyl groups from O(6) methylguanine, and other methylated moities of DNA, to a cysteine residue in itself, thus repairing DNA damage caused by alkylation in a single step reaction. This is a suicide reaction as the enzyme is irreversibly inactivated. MGMT prevents mutagenesis and malignant transformation, and also provides resistance to chemotherapy with alkylating agents among cancer patients. https://www.creative-diagnostics.com/MGMT-peptide-177566-427.htm.



[Related Keywords: Human MGMT peptide ]
 MEP1B peptide 

MEP1B peptide

(October 26, 2018)

Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene

[Related Keywords: MEP1B peptide ]

 Human MEN1 peptide 

Human MEN1 peptide

(October 26, 2018)

This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008]. https://www.creative-diagnostics.com/Menin-peptide-177555-427.htm.



[Related Keywords: Human MEN1 peptide ]
 Human MDM4 peptide 

Human MDM4 peptide

(October 26, 2018)

This gene encodes a nuclear protein that contains a p53 binding domain at the N-terminus and a RING finger domain at the C-terminus, and shows structural similarity to p53-binding protein MDM2. Both proteins bind the p53 tumor suppressor protein and inhibit its activity, and have been shown to be overexpressed in a variety of human cancers. However, unlike MDM2 which degrades p53, this protein inhibits p53 by binding its transcriptional activation domain. This protein also interacts with MDM2 protein via the RING finger domain, and inhibits the latters degradation. So this protein can reverse MDM2-targeted deg

[Related Keywords: Human MDM4 peptide ]

 Human MBD6 peptide 

Human MBD6 peptide

(October 26, 2018)

Binds to heterochromatin. Does not interact with either methylated or unmethylated DNA (in vitro). As a leading supplier of antigens, Creative Diagnostics is proud to offer the highest quality antigens supported by extensive research, development, and validation. We are committed to the highest standards of product performance, and our scientists are dedicated to accelerating your discoveries. https://www.creative-diagnostics.com/MBD6-peptide-177534-427.htm.



[Related Keywords: Human MBD6 peptide ]
 Human MAU2 peptide 

Human MAU2 peptide

(October 26, 2018)

Scc4 (Mau2) is the metazoan homologue of Scc4 in S. cerevisiae. In yeast, Scc4 binds to Scc2 to form an essential complex that loads cohesion onto chromosomes. Similarly, the Scc4 / Mau2 protein in metazoans plays a significant role in sister chromatid separation and in loading of cohesin onto chromatin. The Scc2-Scc4 complex is tethered to pre-replication complexes through the Cdc7-Drf1 protein kinase DDK. https://www.creative-diagnostics.com/Scc4-peptide-177527-427.htm.



[Related Keywords: Human MAU2 peptide ]
 Human MAPK10 peptide 

Human MAPK10 peptide

(October 26, 2018)

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the ph

[Related Keywords: Human MAPK10 peptide ]

 Human MAML1 peptide 

Human MAML1 peptide

(October 26, 2018)

This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway. [provided by RefSeq, Jul 2008]. https://www.creative-diagnostics.com/MAML1-peptide-177514-427.htm.



[Related Keywords: Human MAML1 peptide ]
 Human MAFA peptide 

Human MAFA peptide

(October 26, 2018)

MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene (INS; MIM 176730) (Olbrot et al., 2002 [PubMed 12011435]).[supplied by OMIM, Mar 2008]. https://www.creative-diagnostics.com/MafA-peptide-177511-427.htm.



[Related Keywords: Human MAFA peptide ]
 Mouse MAEL peptide 

Mouse MAEL peptide

(October 26, 2018)

It plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for localization of germ-cell factors to the meiotic nuage. https://www.creative-diagnostics.com/Mael-pep

[Related Keywords: Mouse MAEL peptide ]

 Mouse LY6C1 peptide 

Mouse LY6C1 peptide

(October 26, 2018)

Ly6C is a monocyte/macrophage and endothelial cell differentiation antigen regulated by interferon gamma, and may play a role in the development and maturation of lymphocytes. It is a member of the Ly6 multigene family of type V glycophosphatidylinositol anchored cell surface proteins. It is expressed on bone marrow cells, monocytes/macrophages, neutrophils, endothelial cells, and T cell subsets. Mice with the Ly6.2 allotype (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) have subsets of CD4+Ly6C+ and CD8+Ly6C+ cells, while Ly6.1 strains (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have only CD8+Ly6C+

[Related Keywords: Mouse LY6C1 peptide ]

 LTB4R2 peptide 

LTB4R2 peptide

(October 26, 2018)

Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3. https://www.creative-diagnostics.com/Leukotriene-B4-Receptor-2-peptide-177501-427.htm.



[Related Keywords: LTB4R2 peptide ]
 Human LRPPRC peptide 

Human LRPPRC peptide

(October 26, 2018)

This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome. [provided by RefSeq, Mar 2012]. https://www.creative-diagnostics.com/LRPPRC-peptide-177499-427.htm.&nbs

[Related Keywords: Human LRPPRC peptide ]

 CCT3/TCP1  peptide 

CCT3/TCP1 peptide

(November 26, 2018)

The CCT3/TCP1 peptide encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants have been characterized for this gen

[Related Keywords: Antigen ]

 CD274/PD-L1  peptide 

CD274/PD-L1 peptide

(November 26, 2018)

CD274 (CD274 molecule) is a protein-coding gene. Diseases associated with CD274 include pulmonary venoocclusive disease, and htlv-1 associated myelopathy/tropical spastic paraparesis, and among its related super-pathways are Immune System and Phosphorylation of CD3 and TCR zeta chains. GO annotations related to this gene include protein binding. An important paralog of this gene is PDCD1LG2.



[Related Keywords: CD274/PD-L1 peptide ]
 CD2BP2 (N Terminus)  peptide 

CD2BP2 (N Terminus) peptide

(November 26, 2018)

This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined.



[Related Keywords: CD2BP2 (N Terminus) peptide ]
 CD80  peptide 

CD80 peptide

(November 26, 2018)

The CD80 peptide encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.



[Related Keywords: CD80 peptide ]
 Cdc2 peptide 

Cdc2 peptide

(November 26, 2018)

Transcription of the human cdc2 gene is cell cycle regulated and restricted to proliferating cells. cdc2 transcription is high in S and G2 phases of the cell cycle but low in G1. Creative Diagnostics is an evolving biotech company providing excellent quality antigens worldwide including Viral Antigens, Bacterial Antigens, Fungal Antigens, Parasitic Antigens, Immunoglobulin, Hapten, Cardiac Biomarkers and so on. The antigens of highest quality are rigorously tested to meet the demand in research and development.



[Related Keywords: Cdc2 peptide ]
 CDC37L1/HARC  peptide 

CDC37L1/HARC peptide

(November 26, 2018)

CDC37L1 is a cytoplasmic phosphoprotein that exists in complex with HSP90 (HSPCA; MIM 140571) as well as several other proteins involved in HSP90-mediated protein folding (Scholz et al., 2001 (PubMed 11413142)). Creative Diagnostics is an evolving biotech company providing excellent quality antigens worldwide including Viral Antigens, Bacterial Antigens, Fungal Antigens, Parasitic Antigens, Immunoglobulin, Hapten, Cardiac Biomarkers and so on. The antigens of highest quality are rigorously tested to meet the demand in r

[Related Keywords: Antigen ]

 CDH23/USH1D  peptide 

CDH23/USH1D peptide

(November 26, 2018)

This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice vari

[Related Keywords: CDH23/USH1D peptide ]

 CDT1/Dup  peptide 

CDT1/Dup peptide

(November 26, 2018)

The CDT1/Dup peptide encoded by this gene is involved in the formation of the pre-replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and may function to prevent this protein from initiating replication at inappropriate origins. Phosphorylation of this protein by cyclin A-dependent kinases results in degradation of the protein.



[Related Keywords: CDT1/Dup peptide ]
 Human CDYL blocking peptide 

Human CDYL blocking peptide

(November 26, 2018)

Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone ac

[Related Keywords: Human CDYL blocking peptide ]

 CECR2  peptide 

CECR2 peptide

(November 26, 2018)

CECR2 (cat eye syndrome chromosome region, candidate 2) is a protein-coding gene. Diseases associated with CECR2 include 22q11.2 duplication, and coloboma of iris. GO annotations related to this gene include protein binding and nucleosome-dependent ATPase activity. An important paralog of this gene is BAZ1A.



[Related Keywords: CECR2 peptide ]
 CETP  peptide 

CETP peptide

(November 26, 2018)

Cholesteryl ester transfer protein (CETP) transfers cholesteryl esters between lipoproteins. CETP may effect susceptibility to atherosclerosis. Creative Diagnostics is an evolving biotech company providing excellent quality antigens worldwide including Viral Antigens, Bacterial Antigens, Fungal Antigens, Parasitic Antigens, Immunoglobulin, Hapten, Cardiac Biomarkers and so on. The antigens of highest quality are rigorously tested to meet the demand in research and development.



[Related Keywords: CETP peptide ]
 CHD1 (C Terminus)  peptide 

CHD1 (C Terminus) peptide

(November 26, 2018)

The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template.



[Related Keywords: CHD1 (C Terminus) peptide ]
 CHFR  peptide 

CHFR peptide

(November 26, 2018)

CHFR (checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase) is a protein-coding gene. Diseases associated with CHFR include malignant peripheral nerve sheath tumor, and laryngeal squamous cell carcinoma, and among its related super-pathways are DNA Damage. GO annotations related to this gene include ubiquitin-protein ligase activity and nucleotide binding.



[Related Keywords: CHFR peptide ]
 CHMP5  peptide 

CHMP5 peptide

(November 26, 2018)

CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 1673

[Related Keywords: CHMP5 peptide ]

 CHORDC1 Peptide 

CHORDC1 Peptide

(November 26, 2018)

CHORDC1 (cysteine and histidine-rich domain (CHORD) containing 1) is a protein-coding gene. Diseases associated with CHORDC1 include inclusion conjunctivitis, and conjunctivitis. GO annotations related to this gene include Hsp90 protein binding and zinc ion binding. An important paralog of this gene is ITGB1BP2.



[Related Keywords: CHORDC1 Peptide ]
 CHRNB2  peptide 

CHRNB2 peptide

(November 26, 2018)

Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy.



[Related Keywords: CHRNB2 peptide ]
 Chst5 (mouse)  peptide 

Chst5 (mouse) peptide

(November 26, 2018)

The Chst5 (mouse) peptide encoded by this gene belongs to the Gal/GalNAc/GlcNAc 6-O-sulfotransferase (GST) family, members of which catalyze the transfer of sulfate to position 6 of galactose (Gal), N-acetylgalactosamine (GalNAc), or N-acetylglucosamine (GlcNAc) residues within proteoglycans, and sulfation of O-linked sugars of mucin-type acceptors. Carbohydrate sulfation plays a critical role in many biologic processes. This gene is predominantly expressed in colon and small intestine.



[Related Keywords: Chst5 (mouse) peptide ]
 CILP  peptide 

CILP peptide

(November 26, 2018)

Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for two different proteins; an N-terminal CILP and a C-terminal homolog of NTPPHase, however, later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this pr

[Related Keywords: CILP peptide ]

 CITED2 (Internal)  peptide 

CITED2 (Internal) peptide

(November 26, 2018)

The CITED2 (Internal) peptide encoded by this gene inhibits transactivation of HIF1A-induced genes by competing with binding of hypoxia-inducible factor 1-alpha to p300-CH1. Mutations in this gene are a cause of cardiac septal defects. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.



[Related Keywords: CITED2 (Internal) peptide ]
 CKB/ Brain Creatine Kinase  peptide 

CKB/ Brain Creatine Kinase peptide

(November 26, 2018)

The CKB/ Brain Creatine Kinase peptide encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characteri

[Related Keywords: CKB/ Brain Creatine Kinase peptide ]

 CLCA1   peptide 

CLCA1 peptide

(November 26, 2018)

This CLCA1 peptide encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The enc

[Related Keywords: CLCA1 peptide ]

 CLEC2/CLEC1B  peptide 

CLEC2/CLEC1B peptide

(November 26, 2018)

Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229]).



[Related Keywords: CLEC2/CLEC1B peptide ]
 CLIC4  peptide 

CLIC4 peptide

(November 26, 2018)

Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 4 (CLIC4) protein, encoded by the CLIC4 gene, is a member of the p64 family; the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells).



[Related Keywords: CLIC4 peptide ]
 CLMP  peptide 

CLMP peptide

(November 26, 2018)

The CTX (see VSIG2, MIM 606011) family of proteins, including ASAM, are type I transmembrane proteins within the Ig superfamily that localize to junctional complexes between endothelial and epithelial cells and may play a role in cell-cell adhesion (Raschperger et al., 2004 (PubMed 14573622)).



[Related Keywords: CLMP peptide ]
 Human CLPB blocking peptide 

Human CLPB blocking peptide

(November 26, 2018)

CLPB (ClpB caseinolytic peptidase B homolog (E. coli)) is a protein-coding gene. Diseases associated with CLPB include tularemia, and gastroenteritis. GO annotations related to this gene include nucleoside-triphosphatase activity and molecular_function.



[Related Keywords: Human CLPB blocking peptide ]
 Human CNOT4 blocking peptide 

Human CNOT4 blocking peptide

(November 26, 2018)

The protein encoded by this gene is a subunit of the CCR4-NOT complex, a global transcriptional regulator. The encoded protein interacts with CNOT1 and has E3 ubiquitin ligase activity. Several transcript variants encoding different isoforms have been found for this gene. Creative Diagnostics is an evolving biotech company providing excellent quality antigens worldwide including Viral Antigens, Bacterial Antigens, Fungal Antigens, Parasitic Antigens, Immunoglobulin, Hapten, Cardiac Biomarkers and so on. The antigens of highest

[Related Keywords: Human CNOT4 blocking peptide ]

 Human COG1 blocking peptide 

Human COG1 blocking peptide

(November 26, 2018)

The protein encoded by this gene is one of eight proteins (Cog1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. It is thought that this protein is required for steps in the normal medial and trans Golgi-associated processing of glycoconjugates and plays a role in the organization of the Golgi-localized complex.



[Related Keywords: Human COG1 blocking peptide ]
 COL11A1  peptide 

COL11A1 peptide

(November 26, 2018)

This COL11A1 peptide encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Mutations in this gene are associated with type II Stickler syndrome and with Marshall syndrome. A single-nucleotide polymorphism in this gene is also associated with susceptibility to lumbar disc herniation. Multiple transcript variants have been identified for this gene.



[Related Keywords: COL11A1 peptide ]
 Human COL4A3BP blocking peptide 

Human COL4A3BP blocking peptide

(November 26, 2018)

This COL4A3BP peptide encodes a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. Three transcript variants encoding different isoforms have been found for this gene.



[Related Keywords: Human COL4A3BP blocking peptide ]
 COMT (internal)  peptide 

COMT (internal) peptide

(November 26, 2018)

Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a sol

[Related Keywords: COMT (internal) peptide ]

 Human CFLAR blocking peptide 

Human CFLAR blocking peptide

(December 24, 2018)

The FLIP peptide encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists. [provided by RefSeq, Feb 2011]



[Related Keywords: Human CFLAR blocking peptide ]
 Human FLOT1 blocking peptide 

Human FLOT1 blocking peptide

(December 24, 2018)

Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. FLOT1 encodes a caveolae-associated, integral membrane protein. The function of flotillin 1 has not been determined. [provided by RefSeq, Jul 2008]



[Related Keywords: Human FLOT1 blocking peptide ]
 FLVCR peptide 

FLVCR peptide

(December 24, 2018)

This FLVCR peptide encodes a member of the major facilitator superfamily of transporter proteins. The encoded protein is a heme transporter that may play a critical role in erythropoiesis by protecting developing erythroid cells from heme toxicity. This gene may play a role in posterior column ataxia with retinitis pigmentosa and the hematological disorder Diamond-Blackfan syndrome. [provided by RefSeq, Jan 2011]



[Related Keywords: FLVCR peptide ]
 Human FOXO1 blocking peptide 

Human FOXO1 blocking peptide

(December 24, 2018)

This FOXO1 peptide belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. [provided by RefSeq, Jul 2008]



[Related Keywords: Human FOXO1 blocking peptide ]
 Human FOSL1 blocking peptide 

Human FOSL1 blocking peptide

(December 24, 2018)

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. [provided by RefSeq, Jul 2008].



[Related Keywords: Human FOSL1 blocking peptide ]
 Fumarate hydratase peptide 

Fumarate hydratase peptide

(December 24, 2018)

The Fumarate hydratase peptide encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions a

[Related Keywords: Fumarate hydratase peptide ]

 Fumarate hydratase peptide 

Fumarate hydratase peptide

(December 24, 2018)

The Fumarate hydratase peptide encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions a

[Related Keywords: Fumarate hydratase peptide ]

Human FZD9 blocking peptide  

Human FZD9 blocking peptide

(December 24, 2018)

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD9 gene is located within the Williams syndrome common deletion region of chromosome 7, and heterozygous deletion of the FZD9 gene may contribute to the Williams syndrome phenotype. FZD9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney. [provided by RefSeq, Jul 2008]



[Related Keywords: Human FZD9 blocking peptide ]
 Human PAGR1 blocking peptide 

Human PAGR1 blocking peptide

(December 24, 2018)

C16ORF53 (PA1) is a component of a Set1-like multiprotein histone methyltransferase complex (Cho et al., 2007 [PubMed 17500065]).[supplied by OMIM, May 2008]. Human PAGR1 blocking peptide is for in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not suitable for human or animal consumption.



[Related Keywords: Human PAGR1 blocking peptide ]
 GCC185 peptide 

GCC185 peptide

(December 24, 2018)

The GCC185 peptide encoded by this gene is a peripheral membrane protein localized to the trans-Golgi network. It is sensitive to brefeldin A. This encoded protein contains a GRIP domain which is thought to be used in targeting. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]



[Related Keywords: GCC185 peptide ]
 GCDFP15/PIP peptide 

GCDFP15/PIP peptide

(December 24, 2018)

PIP (prolactin-induced protein) is a protein-coding gene. Diseases associated with PIP include florid papillomatosis of the nipple, and eccrine adenocarcinoma. GO annotations related to this gene include actin binding. For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.



[Related Keywords: GCDFP15/PIP peptide ]
 Human KAT2A blocking peptide 

Human KAT2A blocking peptide

(December 24, 2018)

KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM, Sep 2009].



[Related Keywords: Human KAT2A blocking peptide ]
 GLI1 peptide 

GLI1 peptide

(December 24, 2018)

This GLI1 peptide encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]



[Related Keywords: GLI1 peptide ]
GOLGA6 peptide 

GOLGA6 peptide

(December 24, 2018)

The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. The protein encoded by this gene is a member of the golgin family of proteins, whose members localize to the Golgi. This gene is found in a large, low copy repeat sequence or duplicon that is foun

[Related Keywords: GLP/GOLGA6 peptide ]

 Glutathione Peroxidase 1 (iso1) peptide 

Glutathione Peroxidase 1 (iso1) peptide

(December 24, 2018)

This Glutathione Peroxidase 1 (iso1) peptide encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is c

[Related Keywords: Glutathione Peroxidase 1 (iso1) peptide ]

 Human GYPA blocking peptide 

Human GYPA blocking peptide

(December 24, 2018)

Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene rec

[Related Keywords: Human GYPA blocking peptide ]

 Human GOLM1 blocking peptide 

Human GOLM1 blocking peptide

(December 24, 2018)

The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a type II Golgi transmembrane protein. It processes proteins synthesized in the rough endoplasmic reticulum and assists in the transport of protein cargo through the Golgi apparatus. The expression of this gene has been observed to be upregulated in response to viral infection. Alternatively spliced transcript variants encoding the same protein have been described for this gene

[Related Keywords: Human GOLM1 blocking peptide ]

 GPR119 peptide 

GPR119 peptide

(December 24, 2018)

This GPR119 peptide encodes a member of the rhodopsin subfamily of G-protein-coupled receptors that is expressed in the pancreas and gastrointestinal tract. The encoded protein is activated by lipid amides including lysophosphatidylcholine and oleoylethanolamide and may be involved in glucose homeostasis. This protein is a potential drug target in the treatment of type 2 diabetes.[provided by RefSeq, Jan 2010]



[Related Keywords: GPR119 peptide ]
 Human GPR39 blocking peptide 

Human GPR39 blocking peptide

(December 24, 2018)

GPR39 (G protein-coupled receptor 39) is a protein-coding gene. Diseases associated with GPR39 include obesity, association with, and hyperparathyroidism. GO annotations related to this gene include G-protein coupled receptor activity. An important paralog of this gene is GHSR.



[Related Keywords: Human GPR39 blocking peptide ]
 Human P2RY13 blocking peptide 

Human P2RY13 blocking peptide

(December 24, 2018)

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is activated by ADP. [provided by RefSeq, Sep 2008]. .



[Related Keywords: Human P2RY13 blocking peptide ]
 Grik4 Peptide 

Grik4 Peptide

(December 25, 2018)

This Grik4 Peptide encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [

[Related Keywords: Grik4 Peptide ]

 GRIN2D peptide 

GRIN2D peptide

(December 25, 2018)

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). [provided by RefSeq, Mar 2010].



[Related Keywords: GRIN2D peptide ]
 HEC1 peptide 

HEC1 peptide

(December 25, 2018)

This HEC1 peptide encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation. [provided by RefSeq, Oct 2011]



[Related Keywords: HEC1 peptide ]
 HIP2 peptide 

HIP2 peptide

(December 25, 2018)

The HIP2 peptide encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation.

[Related Keywords: HIP2 peptide ]

 Human DBNL blocking peptide 

Human DBNL blocking peptide

(December 25, 2018)

DBNL (drebrin-like) is a protein-coding gene. Diseases associated with DBNL include cervicitis, and eclampsia. GO annotations related to this gene include actin binding and protein domain specific binding. An important paralog of this gene is DBN1.



[Related Keywords: Human DBNL blocking peptide ]
 Histamine Receptor H2 peptide 

Histamine Receptor H2 peptide

(December 25, 2018)

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript va

[Related Keywords: Histamine Receptor H2 peptide ]

 Human HIVEP2 blocking peptide 

Human HIVEP2 blocking peptide

(December 25, 2018)

This HIVEP2/MIBP1 peptide encodes a member of a family of closely related, large, zinc finger-containing transcription factors. The encoded protein regulates transcription by binding to regulatory regions of various cellular and viral genes that maybe involved in growth, development and metastasis. The protein contains the ZAS domain comprised of two widely separated regions of zinc finger motifs, a stretch of highly acidic amino acids and a serine/threonine-rich sequence. [provided by RefSeq, Nov 2012]



[Related Keywords: Human HIVEP2 blocking peptide ]

 HNF1 alpha peptide 

HNF1 alpha peptide

(December 25, 2018)

The HNF1 alpha peptide encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. [provided by RefSeq, Mar 2009]



[Related Keywords: HNF1 alpha peptide ]
 Hornerin peptide 

Hornerin peptide

(December 25, 2018)

HRNR (hornerin) is a protein-coding gene. Diseases associated with HRNR include irritant dermatitis, and dermatitis. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is RPTN.



[Related Keywords: Hornerin peptide ]
 HP1 gamma peptide 

HP1 gamma peptide

(December 25, 2018)

At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This HP1 gamma peptide also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruite

[Related Keywords: HP1 gamma peptide ]

 TLR8 Peptide 

TLR8 Peptide

(January 23, 2019)

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies

[Related Keywords: TLR8 Peptide ]

 TNFRSF14 Peptide 

TNFRSF14 Peptide

(January 23, 2019)

This gene encodes a member of the TNF (tumor necrosis factor) receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]



[Related Keywords: TNFRSF14 Peptide ]
 TOM70 Peptide 

TOM70 Peptide

(January 23, 2019)

This gene encodes an import receptor of the outer mitochondrial membrane that is part of the translocase of the outer membrane complex. This protein is involved in the import of mitochondrial precursor proteins. [provided by RefSeq, Oct 2011]



[Related Keywords: TOM70 Peptide ]
 TOX Peptide 

TOX Peptide

(January 23, 2019)

The protein encoded by this gene contains a HMG box DNA binding domain. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. This protein may function to regulate T-cell development.[provided by RefSeq, Apr 2009]



[Related Keywords: TOX Peptide ]
TRPC3 (AB1) Peptide 

TRPC3 (AB1) Peptide

(January 23, 2019)

The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]



[Related Keywords: TRPC3 (AB1) Peptide ]
 TRPC6 (AB1) Peptide 

TRPC6 (AB1) Peptide

(January 23, 2019)

The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq, Mar 2009]



[Related Keywords: TRPC6 (AB1) Peptide ]
 TSC1 (AB1) Peptide 

TSC1 (AB1) Peptide

(January 23, 2019)

This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009]



[Related Keywords: TSC1 (AB1) Peptide ]
 TSLP (AB1) Peptide 

TSLP (AB1) Peptide

(January 23, 2019)

This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target

[Related Keywords: TSLP (AB1) Peptide ]

 TSLP Receptor (AB1) Peptide 

TSLP Receptor (AB1) Peptide

(January 23, 2019)

The protein encoded by this gene is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

[Related Keywords: TSLP Receptor (AB1) Peptide ]
 TYW1 Peptide 

TYW1 Peptide

(January 23, 2019)

Wybutosine (yW) is a hypermodified guanosine found in phenylalanine tRNA adjacent to the anticodon that stabilizes codon-anticodon interactions in the ribosome. In yeast, the homolog of this gene is essential for the synthesis of wybutosine. [provided by RefSeq, Dec 2012]



[Related Keywords: TYW1 Peptide ]

HBV type 3 PreS1 (aa 1 - 445) [BSA]

HBV Surface Antigen (subtype ayw, mutation G-145-R)

HBV Active Antigen

Recombinant Hepatitis B E Antigen, His-tagged

HBV Surface Antigen

HCMV Interleukin 10 (aa 26 - 176)

HCMV (AB 32/32) [His]

HCV type 1 Core Antigen (aa 1 - 102)

HCV E2 Protein (aa 383 - 663) [His]

HCV type 1b Nonstructural Protein 5 (aa 2212 - 2313)

HCV Nonstructural Protein 4

HCV type 2 Nonstructural Protein 5

HCV Multiple Antigen (aa 789 - 1867, 2322 - 2423)

HCV E1 protein

HCV type 1a Nucleocapsid Core antigen (aa 2 - 119)

HCV Nonstructural Protein 4 Mosaic (aa 1789 - 1867, 2322 - 2423)

MME peptide

Human MGMT peptide

MEP1B peptide

Human MEN1 peptide

Human MDM4 peptide

Human MBD6 peptide

Human MAU2 peptide

Human MAPK10 peptide

Human MAML1 peptide

Human MAFA peptide

Mouse MAEL peptide

Mouse LY6C1 peptide

LTB4R2 peptide

Human LRPPRC peptide

CCT3/TCP1 peptide

CD274/PD-L1 peptide

CD2BP2 (N Terminus) peptide

CD80 peptide

Cdc2 peptide

CDC37L1/HARC peptide

CDH23/USH1D peptide

CDT1/Dup peptide

Human CDYL blocking peptide

CECR2 peptide

CETP peptide

CHD1 (C Terminus) peptide

CHFR peptide

CHMP5 peptide

CHORDC1 Peptide

CHRNB2 peptide

Chst5 (mouse) peptide

CILP peptide

CITED2 (Internal) peptide

CKB/ Brain Creatine Kinase peptide

CLCA1 peptide

CLEC2/CLEC1B peptide

CLIC4 peptide

CLMP peptide

Human CLPB blocking peptide

Human CNOT4 blocking peptide

Human COG1 blocking peptide

COL11A1 peptide

Human COL4A3BP blocking peptide

COMT (internal) peptide

Human CFLAR blocking peptide

Human FLOT1 blocking peptide

FLVCR peptide

Human FOXO1 blocking peptide

Human FOSL1 blocking peptide

Fumarate hydratase peptide

Fumarate hydratase peptide

Human FZD9 blocking peptide

Human PAGR1 blocking peptide

GCC185 peptide

GCDFP15/PIP peptide

Human KAT2A blocking peptide

GLI1 peptide

GOLGA6 peptide

Glutathione Peroxidase 1 (iso1) peptide

Human GYPA blocking peptide

Human GOLM1 blocking peptide

GPR119 peptide

Human GPR39 blocking peptide

Human P2RY13 blocking peptide

Grik4 Peptide

GRIN2D peptide

HEC1 peptide

HIP2 peptide

Human DBNL blocking peptide

Histamine Receptor H2 peptide

Human HIVEP2 blocking peptide

HNF1 alpha peptide

Hornerin peptide

HP1 gamma peptide

TLR8 Peptide

TNFRSF14 Peptide

TOM70 Peptide

TOX Peptide

TRPC3 (AB1) Peptide

TRPC6 (AB1) Peptide

TSC1 (AB1) Peptide

TSLP (AB1) Peptide

TSLP Receptor (AB1) Peptide

TYW1 Peptide

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